The operating system for human performance.

The world's first continuously learning model of how people and organizations perform under real operational stress.

Converting physiology into cognitive intelligence that protects performance when decisions carry consequences.

Pre-Seed Round
$750K

Deploys against contracted and near-term pipeline

Seed round target $2.5M · Q1 2027

Confidential & proprietary · Not an offer of securities

The Numbers

Operational risk you can already price.

Five reasons this is a balance-sheet problem, not a wellness one.

4.5M+
High-consequence professionals (US)
$4.6B
Annual US physician burnout cost
23%
Adverse events linked to cognitive failure
$1M+
Avg. cost per serious adverse event
0
Platforms solving this at organizational scale
The Problem: Operational Risk, Not Wellness

Hours-based policy substitutes for measurement.

Organizations deploy physicians, pilots, military officers, and first responders with no systematic understanding of their cognitive state. The result: preventable harm and burnout stay invisible until they become an incident.

Why now: HRV sensing has reached clinical grade, and person-level AI can finally recalibrate continuously to each individual, not population averages.

Hidden capacity: Seren reveals human capacity that conventional performance metrics never detect: fatigue, decline, and readiness invisible to any dashboard today.
A New Category

Cognitive Performance Intelligence

Consumer wellnessClinical diagnosticsAn EAP

WHOOP and Oura track fitness recovery. Seren transforms physiology into cognitive intelligence, reading cognitive load in a surgeon at hour six.

Sense
Interpret
Infer
Guide
Learn
Most systems

Explain yesterday.

Seren

Forecasts tomorrow.

Traditional software follows rules. Seren discovers relationships between physiology and performance that humans never explicitly modeled. Explainable by design: most recommendations include an evidence trace explaining why Seren reached its conclusion.

Physiology
Intelligence
Better Decisions
Better Organizations
Market Opportunity: Beachhead, No Competitor at Scale

A $74B category, entering through its highest-pain door.

Beachhead: physicians & surgeons (950K), active-duty military (1.33M), fire/EMS/police (1.4M), and certificated pilots (633K), professions where cognitive failure carries quantifiable legal, financial, and human consequences.

$74B
TAM · Global OPI by 2032
$18B
SAM · US high-value sectors
$4.2B
SOM Y1 · US healthcare entry
The Moat: Experience, Not Technology

Wearables optimize fitness. Seren optimizes human performance when decisions carry consequences.

No one else has spent a decade watching physicians, police officers, and other high-consequence professionals make thousands of real decisions under real stress. Not HRV. Not AI. Not wearables. Experience.

Seren doesn't simply remember your physiology. It remembers how you perform.

SaaS depreciates. Seren appreciates. That experience compounds. Every organization that runs on it becomes harder to replace than the day before.

The flywheel: every user improves the model. Every shift improves the individual. Every organization improves the platform.

100M+ physiological measurements collected during real operational stress  · 200+ clinicians, ER physicians & police  · 10+ yrs of accumulated experience
The Team

Built by the combination this requires.

Seren brings together decades of leadership in AI, enterprise software, and frontline medicine.

Advisory board: Occupational Medicine Chair (Top-10 medical school) · Former CMO, major health system · Founding Partner, health-tech VC · Former military-medicine leadership.

Stephen Mase

Stephen Mase

Chief Executive Officer

40 years building AI, analytics, and fintech companies. Multiple successful startups; last exit $155M.

Joel Carter

Joel Carter

Chief Science Officer

Harvard-trained physician leader with 20+ years of clinical innovation. TEDx speaker on physician resilience.

Paul Wetzel

Paul Wetzel

Chief Technology Officer

20+ years building and scaling enterprise SaaS. Multi-time CTO across fintech, healthcare, and AI.

Get in Touch

Let's talk.

The fastest way to reach us.

Confidential & proprietary · Not an offer of securities